Sierra Vaughn: "Jacksonville had no business losing this game. The Jaguars outgained Indianapolis by 16 yards and won the air battle by 38, but gave the ball away twice while the Colts didn't give it up once — and that single variable flipped a game that should've gone the other way."

Take care of the football or lose. Jaguars did not, and did. Brian Thomas Jr was the target for Jaguars — 3 catches, 82 yards, 2 TD — in a losing effort. Jonathan Taylor did the work on the ground for Colts — 14 carries, 115 yards, 1 TD. A lean spell for Jonathan Taylor, whose last three have averaged 75 rushing yards against a season figure of 110. On the ground: Colts 185, Jaguars 131.

A long afternoon for Bengals. Colts by 22. Anthony Richardson Sr did the damage for Colts — 24/36, 290 yards, 2 TD, 1 INT. Alec Pierce did the catching for Colts — 7 catches, 105 yards. Anthony Richardson Sr's high-water mark for the year. Total yards: Colts 408, Bengals 281.

Giants took care of Colts, 21-17. Cam Skattebo ran it for Giants — 25 carries, 174 yards, 3 TD. Jonathan Taylor did the work on the ground for Colts — 14 carries, 101 yards, 1 TD — in a losing effort. That is 3 straight games over 100 for Jonathan Taylor. Total yards: Giants 316, Colts 205.

Dolphins could not stop handing it over, and Colts made it count — 30-15. Jonathan Taylor did the work on the ground for Colts — 13 carries, 107 yards, 1 TD. Greg Dulcich did the catching for Dolphins — 6 catches, 77 yards — in a losing effort. Three weeks of this now from JT Tuimoloau: 1 sacks a game, well clear of his 1 average. On the ground: Colts 203, Dolphins 117.

A long afternoon for Colts. Cowboys by 31. Dak Prescott was steady for Cowboys — 13/21, 319 yards, 3 TD. George Pickens did the catching for Cowboys — 5 catches, 115 yards, 3 TD. Dak Prescott has now cleared 250 passing yards in 5 in a row. Through the air: Cowboys 319, Colts 152.

Colts could not stop handing it over, and Ravens made it count — 24-16. Lamar Jackson threw for Ravens — 22/35, 224 yards, 2 TD. DJ Giddens carried the load for Colts — 11 carries, 102 yards, 2 TD — in a losing effort. Total yards: Ravens 485, Colts 287.

The Texans dominated the Colts 49-30 in Week 3, with C.J. Stroud completing 19 of 26 passes for 375 yards and 7 touchdowns against 2 interceptions. Marlin Klein caught 10 passes for 196 yards and 3 scores as Houston's passing attack overwhelmed Indianapolis, which managed only 236 passing yards from Anthony Richardson Sr despite 217 rushing yards on the ground. Houston's defense recorded 4 sacks while the Colts failed to record any, and the Texans forced 3 giveaways to Houston's 2. The win improves Houston to 4-2 while Indianapolis falls to 1-6.